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I have pain in the upper right quadrant of my stomach around the liver. I have had an Upper G.I. & a Lower G.I.. I also, had a Colonoscopy and several CAT scans of Liver, and Ultrasound of Liver. The Ultrasound found an Enlarged-Liver. I had two Liver Biopsies: both found inflammation of Liver? Tested for Porphyria, Lupus and several other diseases: all tests were negative. My CBC is always a different count: one time red is high and white is low, then white is high and red is low never normal. I have Osteoarthritis of both my feet, knees and neck.

I also have severe Varicose veins in both legs.

I had my gallbladder removed, Biopsy showed chronic inflammation.

I have been unable to work since I got sick on 10/23/94, I had some kind of virus or something that caused a 105 fever for about 1 ½ weeks, and solidified 35% of my veins in left leg. They put me in the hospital on 11/14/94, and put me on heavy doses of antibiotics and heparin. At the same time I told my Doctors, about the pain in my stomach, I was told not to worry about it. My Doctors did not start treating or testing me for my stomach pain until March, 1995.

(They do not what kind of VIRUS or what ever I had.)

 

In March, 1993 I told my doctor of pain in the upper right quadrant of my stomach and chest.

The doctor said I pulled a stomach muscle, from carrying my camera bag. (I am a Professional Photographer, and I did all my own B&W processing and printing, and I did R&D in my darkroom.)

In March 1994 same thing pain in the upper right quadrant of my stomach and chest and in right arm.

I am a White Male, age 52.

My Symptoms are:

  1. Fatigue

  2. Rash on both forearms with little red blood blisters also little red blood blisters on top of both feet.

  3. Very high sensitivity to the sun / heat: because of this, I stay inside.

  4. Loss of weight and loss of appetite I make myself eat at least once a day.

  5. Feel sleepy all the time.

  6. Pain in upper right quadrant around liver when walking, coughing, sitting and driving.

  7. Mucous and blood from rectum.

  8. Breathing is very hard at times.

  9. Hard time walking up and down steps.

     10. For over two years now I have been unable to wear shoes, for my feet sweet and swell up and turn red on bottom and sides.

     11. The more I move around the more pain I have in URQ, and if I bend over it feels like  something is pushing up into my right lung

     12. High eye sensitivity to sun

     13. A fowl taste in mouth, like an abscesses but I have upper and lower dentures and at times my mouth tastes tinny.

     14. My Left leg is hurting more and more, right leg hurting but as much.

Radiology Report, RT Shoulder, Humerus, Hand, Foreman & Elbow 3/28/94

Multiple views of the right arm were obtained. There is no fracture or dislocation. Evaluation of the shoulder reveals sclerosis in the region of the greater tuberosity of the humerus, most likely related to tendinitis. No calcification is present in soft tissues in this region. A bony sour is present in the distal humerus, anteromedially.

IMPRESSION, Tendinitis at the insertion of the rotator cuff tendon.

Radiology Report, Chest PA and Lateral, 11/3/94

The lung fields are satisfactorily aerated. There is no pleural effusion. The trachea is undisplaced and the hilar shadows are normal. The diaphragm is well arched. The heart and great vessels are unremarkable. The left 1st. Rib has been resected.

IMPRESSION, No evidence of recent or active pulmonary disease. Aside from the absent left 1st rib, the chest is unremarkable.

Admission to Hospital, 11/14/94 - Discharged 11/26/94 (Vascular Surgeon Report)

Diagnosis: Thrombophlebitis of left lower extremity.

Hospital Course:

Patient placed on intravenous antibiotics, consisting of Ancef, was started on Heparin therapy for anticoagulation, however, prescribed bed rest and warm compresses to lower extremity.
Initially patient did well with the regimen which showed marked improved initially on this regimen. However, several days into his course, his phlebitis came back. This is on 11/18/94.
His examination changed which included increased pain and increasing erythema. At that time it was decided to change his intravenous antibiotics. The patient was placed on Unasyn at 1.5 mgs.

q. six hours. Also, patient in hospital was anticoagulated with Heparin drip and started on Coumadin therapy to get his PT in the therapeutic range.

Medication On Discharge: 1. Augmentin 500 mgs. 1 po. t.i.d. for 14 days.

2. Coumadin 2.5 mgs. daily until further advised.

Radiology Report, Barium Enema - Air Contrast, 3/23/95

The entire colon was well visualized. No concentric lesion, polyps, ulcerations nor other mucosal abnormalities are demonstrated. Some diverticula are noted. No other significant findings are seen.

CONCLUSION, Mild diverticulosis. Tics predominantly in sigmoid and descending colon.

Radiology Report, Upper G.I. Series with KUB, 4/3/95

Preliminary scout film of the abdomen demonstrates no evidence of radiopaque densities to suggest calculi. The intestinal gas pattern is within normal limits. There are several small areas of retained barium in colonic diverticula from a recent barium enema.

A small hiatal hernia is identified. No reflux was noted during the study. No changes of esophagitis are seen. The stomach and duodenum are normal. No other significant finding are noted.

CONCLUSION, Small hiatal hernia.

Radiology Report, B-Scan ABD Complete, 5/1/95

The length of the right hepatic lobe is 19.26cm, indicating mild hepatomegaly. There is slight decrease in the visualization of the peripheral portal venous vasculature raising the question of a chronic hepatic inflammatory process vs a small amount of fatty infiltration. Please correlate clinically. The gallbladder was appropriately distended without thickening of the wall, pericholecystic fluid or contained sludge or stones. The region of the gallbladder is where Mr. Haggerty reports his primary discomfort, and therefore acalculus CHOLECYSTITIS cannot be excluded. The right kidney appears normal. The pancreatic duct is top normal size but the pancreas is otherwise unremarkable.

IMPRESSION, Mild hepatomegaly with slightly abnormal liver texture raising the question of fatty infiltration and/or a mild chronic hepatic inflammatory process. Normal appearing gallbladder with pain centered over the gallbladder raising the question of acalculus CHOLECYSTITIS.

Associate Director, Center for liver Disease. 5/26/96

Mr. Haggerty's main risk factor for liver disease is alcohol. He was a heavy drinker up until 1980. He drank on a daily basis, mostly scotch. He denies any history of hepatitis or jaundice (neonatal or otherwise), blood transfusions, IV drug abuse, occupational exposure to blood or bodily fluids, or family history of liver disease.

Impression:

1. Hepatomegaly of unknown cause.

2. History of rectal bleeding.

3. History of hematemesis.

4. History of duodenal ulcer.

Plan:

1. Presence of hepatomegaly indicates hepatic pathology. I explained to Mr. Haggerty that he will need a liver biopsy to accurately access the severity and etiology of liver disease. He will need viral serologies, iron indices, autoimmune panel, alpha-1-antitrypsin level, etc. I will do a liver biopsy when these results are obtained and Coumadin is stopped.

2. The patient should have a sigmoidoscopy to evaluate rectal bleeding. While it is most likely due to hemorrhoids, other causes will be investigated.

Radiology Interpretation, 6/24/95

Radiology Report,

On the preliminary scout film of abdomen there is prominent loops of small bowel throughout the abdomen. The large bowel is nondistended. There are no radiopaque densities to suggest calculi. There are several phleboliths within pelvis.

60cc of isovue was injected intravenously. There is satisfactory excretion of the contrast material from the kidneys after injection. The right renal collecting system appears normal without evidence of intrarenal masses or obstruction. The infundibulum of the left renal collecting system appears elongated with poor opacification of the renal pelvis.

Segments of the ureters are outlined and these appear normal in caliber and not displaced.

No abnormalities of the urinary bladder are identified.

Impression:

there is no evidence of hydronephrosis or obstructing calculi. There is however left renal collecting system abnormalities as described above suggesting a cystic or solid renal mass. An ultrasound is suggested for further evaluation.

Surgical Pathology Report

Date of Surgery: 07/05/95 Accession: SP-95-04606

Clinical Diagnosis/History:

50 year old white male of Irish descent with hepatomegaly. History of excessive ETOH use. Stopped for many years. Serology for hepatitis B, C negative. Rule out chronic active hepatitis. Rule out hemochromatosis.

Macroscopic Description:

The specimen is received in two parts, both labeled "LIVER".

The first part is received in formalin. It consists of a thin, elongated piece of soft tan tissue measuring .3 cm length x .1 cm in greatest diameter. SUBMITTED IN TOTO ONE PIECE IN CAP A1.

The second part is received fresh in a glass container. It consists of a .4 x .2 cm piece of soft liver tissue. The specimen is saved in deep freeze for possible further studies.

mb M. MILCU, M.D./SN

Microscopic Description:

The section above shows liver parenchyma with preservation of the usual architecture. Portal spaces are not expanded. There is no evidence of portal inflammation nor piece-meal necrosis. A few small collections of benign mononuclear cells, mostly lymphocytes, are seen in the liver parenchyma; some of these are located adjacent to central vein. The sinusoids are dilated in some areas. The hepatocytes show slight focal regenerative changes. There is no bile duct proliration. Fibrosis is not seen. Bile stasis is not noted. Special stain for iron demonstrates minimal iron.

Special Stains:

IRON

Diagnosis:

LIVER BIOPSY: LIVER TISSUE WITH FOCAL REGENERATIVE CHANGES AND

MINIMAL, CHRONIC INFLAMMATION OF UNCERTAIN ORIGIN. FOLLOWUP

AND CLINICO-PATHOLOGIC CORRELATION IS SUGGESTED.

T56000, P11400, M43000

Comment:

A verbal report given to Dr. Rothstein on July 6th 1995.

MM MARIA MILCU M.D.

____________________________

07/10/95 (Electronic Signature)

Print Date/Time 07/11/95 0216 Page Number: 1

Radiology Report, B-Scan ABD Complete, B-Scan Flow ABS/Pelvic Organs 09:05 7/20/95

Ultrasound of the abdomen and duplex color Doppler of the biliary vessels was performed. The previous sonogram is not locatable at this time and thus the report is rendered in comparison with my previous report of the sonogram performed 5/1/95. The Liver remains mildly enlarged and appears to be slightly smaller than on the pervious examination with the length of the right lobe in the mid clavicular line now measuring 16.2 cm. There is no evidence of intra or extrahepatic bile duct ectrasia and the gallbladder appears normal. The liver texture remains abnormal with moderate decrease in the visualization of the peripheral portal venous vasculature which is a nonspecific finding which could be associated with a chronic inflammatory process or deposition of dense material such as fat or fibrous tissue. The spleen is not enlarged measuring 9.9 cm in length. There was no evidence of ascites. The hepatic artery, hepatic veins, portal vein, splenic vein and IVC were examined with duplex color Doppler ultrasound and appropriate antegrade flow was observed in all of the vessels insonated.

Impression: Chronic hepatic inflammatory process vs deposition of dense material such as fat or fibrous tissue. No Doppler evidence of portal hypertension or Budd-Chiari syndrome.

Radiology Report, NM Bone Scan-Whole Body, 6/26/96

Following intravenous administration of 28.3 mci of technetium 99m MDP, whole body bone images were performed.

There is increased, focal radiotracer uptake in region of the tarsal bones in left foot and in the region of the 1st metatarsal phalangeal joint of right foot which corresponds to osteoarthritic changes seen on recent radiographs in these areas. There is a tiny focus of radiotracer uptake overlying the lateral superior edge of the left orbital rim, seen on the anterior view and not seen on lateral view, which is probably clinically insignificant. No other abnormal areas of radiotracer accumulation are noted.

IMPRESSION, Degeneration changes in both feet as described above.

Surgical Pathology Report

Date of Surgery: 01/11/96 Accession: SP-96-00202

Clinical Diagnosis/History:

Fifty-one year old white male with abdominal pain and constipation.

Hepatomegaly.

Macroscopic Description:

The specimen is labeled "DESCENDING COLON POLYP" and it is received in

formalin. It consists of several fragments of soft pink-tan tissue ranging from 1 mm up to

3 mm in maximum dimensions. SUBMITTED IN TOTO CAP A1.

mb N. ZAERI, M.D./SN

Diagnosis:

DESCENDING COLON POLYP:

TWO COLONIC BIOPSIES WITH SLIGHT HYPEREMIA AND INCREASED

PROPARIAL CELLULARITY, TWO SMALL FRAGMENTS WITH SEVERE

ARTIFACT WITH FEATURES OF POSSIBLE HYPERPLASTIC POLYP.

T67600, M76800, P11400, M36110, M09030, M72040

BH NAYERE ZAERI, M.D..

_______________________

01/12/96 (Electronic Signature)

Print Date/Time 01/13/96 0134 Page Number: 1

Surgical Pathology Report

Date of Surgery: 02/01/96 Accession: SP-96-00681

Clinical Diagnosis/History:

None given.

Macroscopic Description:

The specimen is labeled "LIVER BIOPSY" and consists of a wedge of liver tissue that

measures 2.5 x 0.5 cm in maximum extent. The capsular surface appears to be smooth

and glistening. TWO SECTIONS SUBMITTED IN ONE CAP.

Subsequent received is a specimen labeled "GALLBLADDER" and received in formalin.

It consists of a collapsed gallbladder and measures 6.0 x 3.2 x 1.5 cm. The surface is

smooth. The lumen contains a small amount of bile. The mucosa is congestive. The

wall averages 0.5 cm. REPRESENTATIVE SECTIONS SUBMITTED IN CAP B1.

mb/bh N. ZAERI, M.D.

Microscopic Description:

The open wedge biopsy of liver shows generally preserved acinar architecture. Portal

areas are essentially devoid of any significant inflammatory infiltrate except for a single

portal area with a rather dense lymphoplasmacytic infiltrate blurring the limiting plate and

the portal components. Also noted is focal steatosis adjacent to this infiltrate. The

remaining parenchyma shows scattered large nuclei, double nucleated hepatocytes

indicative of some regenerating activity. The overall histopathologic findings of liver is

essentially similar to the previous biopsy (7/5/95). The exact nature of this focal lympho-

plasmacytic infiltrate is not clear, and no specific diagnosis can be offered based on

histology alone.

Diagnosis:

LIVER WEDGE BIOPSY:

FOCAL PORTAL LYMPHOPLASMACYTIC INFILTRATE AND

STEATOSIS WITH SOME REGENERATING ACTIVITY THROUGHOUT.

NO SPECIFIC DIAGNOSIS CAN BE MADE. CLINICAL CORRELATION IS

ADVISABLE.

GALLBLADDER:

CHRONIC CHOLECYSTITIS.

T56000, P11400, M50080, M00100, T57000, M43000

Print Date/Time 02/13/96 0125 Page Number: 1

On 8/13/96 I was tested for Lyme Disease and I am waiting for the report.

Report on Lyme Disease Negative.

 

 

 

 

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